If you are running ITunes on a windows machine, it is probably the biggest resource hog. Here are some tips to speed it up.
Delete the playlists above. Delete all Playlists that are in Purple. It takes ITunes a lot of resources to keep these up to date. So if you never use them, get rid of them.
Go to the preferences and uncheck everything. Don’t look for shared libraries.
Don’t look for Apple TV’s.
Don’t look for remote speakers.
Get the point, you don’t want ITunes to look for any of this stuff, it takes up memory. Uncheck it all.